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Kombinasjon med andre medisiner/kosttilskudd: Opioider kan gi forstoppelse og dette kan påvirke opptak av andre medisiner. Snakk med farmasøyt eller lege om medisiner du bruker fra før, eller ved oppstart av nye medisiner. Faglige anbefalinger for udredning og behandlingsbehov hos patienter med kroniske smerter i almen praksis.Metadon (Metadon)